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. 2015 Jan;26(1):31-7.
doi: 10.1681/ASN.2014111057. Epub 2014 Nov 14.

Successful delivery of RRT in Ebola virus disease

Affiliations

Successful delivery of RRT in Ebola virus disease

Michael J Connor Jr et al. J Am Soc Nephrol. 2015 Jan.

Abstract

AKI has been observed in cases of Ebola virus disease. We describe the protocol for the first known successful delivery of RRT with subsequent renal recovery in a patient with Ebola virus disease treated at Emory University Hospital, in Atlanta, Georgia. Providing RRT in Ebola virus disease is complex and requires meticulous attention to safety for the patient, healthcare workers, and the community. We specifically describe measures to decrease the risk of transmission of Ebola virus disease and report pilot data demonstrating no detectable Ebola virus genetic material in the spent RRT effluent waste. This article also proposes clinical practice guidelines for acute RRT in Ebola virus disease.

Keywords: AKI; Ebola virus disease; biocontainment isolation; continuous RRT.

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References

    1. Clark DV, Jahrling PB, Lawler JV: Clinical management of filovirus-infected patients. Viruses 4: 1668–1686, 2012 - PMC - PubMed
    1. Rollin PE, Bausch DG, Sanchez A: Blood chemistry measurements and D-Dimer levels associated with fatal and nonfatal outcomes in humans infected with Sudan Ebola virus. J Infect Dis 196[Suppl 2]: S364–S371, 2007 - PubMed
    1. Smith PW, Anderson AO, Christopher GW, Cieslak TJ, Devreede GJ, Fosdick GA, Greiner CB, Hauser JM, Hinrichs SH, Huebner KD, Iwen PC, Jourdan DR, Kortepeter MG, Landon VP, Lenaghan PA, Leopold RE, Marklund LA, Martin JW, Medcalf SJ, Mussack RJ, Neal RH, Ribner BS, Richmond JY, Rogge C, Daly LA, Roselle GA, Rupp ME, Sambol AR, Schaefer JE, Sibley J, Streifel AJ, Essen SG, Warfield KL: Designing a biocontainment unit to care for patients with serious communicable diseases: A consensus statement. Biosecur Bioterror 4: 351–365, 2006 - PubMed
    1. Forrester JD, Hunter JC, Pillai SK, Arwady MA, Ayscue P, Matanock A, Monroe B, Schafer IJ, Nyenswah TG, De Cock KM: Cluster of Ebola cases among Liberian and U.S. health care workers in an Ebola treatment unit and adjacent hospital - Liberia, 2014. MMWR Morb Mortal Wkly Rep 63: 925–929, 2014 - PMC - PubMed
    1. Fowler RA, Fletcher T, Fischer WA, 2nd, Lamontagne F, Jacob S, Brett-Major D, Lawler JV, Jacquerioz FA, Houlihan C, O’Dempsey T, Ferri M, Adachi T, Lamah MC, Bah EI, Mayet T, Schieffelin J, McLellan SL, Senga M, Kato Y, Clement C, Mardel S, Vallenas Bejar De Villar RC, Shindo N, Bausch D: Caring for critically ill patients with ebola virus disease. Perspectives from West Africa. Am J Respir Crit Care Med 190: 733–737, 2014 - PubMed

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