Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Oct 17;2014(5):65-75.
doi: 10.2147/RRTM.S44274.

Prevention and control of schistosomiasis: a current perspective

Marianette T Inobaya  1 , Remigio M Olveda  1 , Thao Np Chau  2 , David U Olveda  3 , Allen Gp Ross  3
Affiliations

Prevention and control of schistosomiasis: a current perspective

Marianette T Inobaya et al. Res Rep Trop Med. .

Abstract

Schistosomiasis is a neglected tropical disease that ranks second only to malaria in terms of human suffering in the tropics and subtropics. Five species are known to infect man and there are currently over 240 million people infected worldwide. The cornerstone of control to date has been mass drug administration with 40 mg/kg of praziquantel but there are problems with this approach. Human and bovine vaccines are in various stages of development. Integrated control, targeting the life cycle, is the only approach that will lead to sustainability and future elimination.

Keywords: mass drug administration; morbidity; schistosomiais; treatment and control.

PubMed Disclaimer

Conflict of interest statement

The authors report no conflicts of interest in this work. Ethical clearance was not required for this review.

Figures

Figure 1
Figure 1
Worldwide geographical distribution of schistosomiasis in 2010. Note: Copyright © 2013 World Health Organization. Reproduced, with the permission of the publisher, from Schistosomiasis Progress Report (2001–2011) and Strategic Plan (2012–2020), Geneva, World Health Organization, 2013. Available from: http://www.who.int/schistosomiasis/resources/en/. Accessed December 9, 2013.1
Figure 2
Figure 2
Life cycle of schistosome species. Note: From The New England Journal of Medicine: Ross AG, Bartley PB, Sleigh AC, et al. Schistosomiasis. 2002;346(16):1212–1220. Copyright © 2002 Massachusetts Medical Society. Reprinted with permission from Massachusetts Medical Society.17
See this image and copyright information in PMC

References

    1. World Health Organization. Schistosomiasis Progress Report (2001−2011) and Strategic Plan (2012−2020). Geneva, Switzerland: World Health Organization Press; 2013. Available from: http://www.who.int/schistosomiasis/resources/en/. Accessed December 9, 2013.
    1. Barry MA, Simon GG, Mistry N, Hotez PJ. Global trends in neglected tropical disease control and elimination: impact on child health. Arch Dis Child. 2013;98(8):635–641. - PubMed
    1. Mathers CD, Ezzati M, Lopez AD. Measuring the burden of neglected tropical diseases: the global burden of disease framework. PLoS Negl Trop Dis. 2007;7:1(2):e114. - PMC - PubMed
    1. World Health Organization. The global burden of disease: 2004 update. Geneva, Switzerland: World Health Organization Press; 2008. Available from: http://www.who.int/healthinfo/global_burden_disease/2004_report_update/en/. Accessed July 16, 2014.
    1. King CH. Parasites and poverty: the case of schistosomiasis. Acta Trop. 2010;113(2):95–104. - PMC - PubMed

LinkOut - more resources