Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014:2014:953451.
doi: 10.1155/2014/953451. Epub 2014 Oct 14.

Antitumor activity of monoterpenes found in essential oils

Affiliations
Review

Antitumor activity of monoterpenes found in essential oils

Marianna Vieira Sobral et al. ScientificWorldJournal. 2014.

Abstract

Cancer is a complex genetic disease that is a major public health problem worldwide, accounting for about 7 million deaths each year. Many anticancer drugs currently used clinically have been isolated from plant species or are based on such substances. Accumulating data has revealed anticancer activity in plant-derived monoterpenes. In this review the antitumor activity of 37 monoterpenes found in essential oils is discussed. Chemical structures, experimental models, and mechanisms of action for bioactive substances are presented.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Hanahan D., Weinberg R. A. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646–674. doi: 10.1016/j.cell.2011.02.013. - DOI - PubMed
    1. Brasil Ministério da Saúde, Instituto Nacional de Câncer . Políticas e Ações para Prevenção do Câncer no Brasil Alimentação, Nutrição e Atividade Física. Rio de Janeiro, Brazil: INCA; 2009.
    1. Pita J. C. L. R., Xavier A. L., de Sousa T. K. G., Mangueira V. M., Tavares J. F., de Oliveira Júnior R. J., Veras R. C., Pessoa H. L. F., Silva M. S., Morelli S., R V. M., Silva T. G., Diniz M. F. F. M., Castello-Branco M. V. S., Oliveira Júnior R. J., Ávila V. M. R. In vitro and in vivo antitumor effect of trachylobane-360, a diterpene from Xylopia langsdorffiana. Molecules. 2012;17(8):9573–9589. doi: 10.3390/molecules17089573. - DOI - PMC - PubMed
    1. Efferth T. Cancer therapy with natural products and medicinal plants. Planta Medica. 2010;76:1035–1036. doi: 10.1055/s-0030-1250062. - DOI - PubMed
    1. De Sousa D. P. Medicinal Essential Oils: Chemical, Pharmacological and Therapeutic Aspects. 1st. New York, NY, USA: Nova Science Publishers; 2012.

Publication types

MeSH terms