Antitumor activity of monoterpenes found in essential oils
- PMID: 25401162
- PMCID: PMC4220615
- DOI: 10.1155/2014/953451
Antitumor activity of monoterpenes found in essential oils
Abstract
Cancer is a complex genetic disease that is a major public health problem worldwide, accounting for about 7 million deaths each year. Many anticancer drugs currently used clinically have been isolated from plant species or are based on such substances. Accumulating data has revealed anticancer activity in plant-derived monoterpenes. In this review the antitumor activity of 37 monoterpenes found in essential oils is discussed. Chemical structures, experimental models, and mechanisms of action for bioactive substances are presented.
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References
-
- Brasil Ministério da Saúde, Instituto Nacional de Câncer . Políticas e Ações para Prevenção do Câncer no Brasil Alimentação, Nutrição e Atividade Física. Rio de Janeiro, Brazil: INCA; 2009.
-
- Pita J. C. L. R., Xavier A. L., de Sousa T. K. G., Mangueira V. M., Tavares J. F., de Oliveira Júnior R. J., Veras R. C., Pessoa H. L. F., Silva M. S., Morelli S., R V. M., Silva T. G., Diniz M. F. F. M., Castello-Branco M. V. S., Oliveira Júnior R. J., Ávila V. M. R. In vitro and in vivo antitumor effect of trachylobane-360, a diterpene from Xylopia langsdorffiana. Molecules. 2012;17(8):9573–9589. doi: 10.3390/molecules17089573. - DOI - PMC - PubMed
-
- De Sousa D. P. Medicinal Essential Oils: Chemical, Pharmacological and Therapeutic Aspects. 1st. New York, NY, USA: Nova Science Publishers; 2012.
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