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Randomized Controlled Trial
. 2014 Nov;16(11):1105-8.

[Preventive effect of behavioral therapy plus flunarizine in children with migraine]

[Article in Chinese]
Yan-Zhao Chen  1 , Ning Li, Ke-Ying Zhou
Affiliations
  • PMID: 25406552
Free article
Randomized Controlled Trial

[Preventive effect of behavioral therapy plus flunarizine in children with migraine]

[Article in Chinese]
Yan-Zhao Chen et al. Zhongguo Dang Dai Er Ke Za Zhi. 2014 Nov.
Free article

Abstract

Objective: To investigate the preventive effect of behavioral therapy plus flunarizine in children with migraine.

Methods: Ninety pediatric patients with migraine between January 2011and January 2014 were randomly divided into treatment group (45 cases) and control group (45 cases). The treatment group received behavioral therapy in addition to oral flunarizine, while the control group received oral flunarizine alone. All patients were followed up for 3 months to evaluate the therapeutic effect by the Pediatric Migraine Disability Assessment Score (PedMIDAS) and improved Bussone headache index.

Results: There were no significant differences in PedMIDAS (P>0.05) and improved Bussone headache index (P>0.05) between the control and treatment groups before treatment. Significant differences were observed in PedMIDAS (16±8 vs 20±10; P<0.05) and improved Bussone headache index (25±18 vs 37±21; P<0.05) between the two groups after 3 months of treatment.

Conclusions: Preventive treatment of behavioral therapy plus oral flunarizine shows a better clinical efficacy than oral flunarizine alone in children with migraine and holds promise for clinical application.

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