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Review
. 2014 Sep 15;7(3):349-57.
Epub 2014 Sep 25.

Endometriosis still a challenge

C Mehedintu  1 , M N Plotogea  1 , S Ionescu  1 , M Antonovici  1
Affiliations
Review

Endometriosis still a challenge

C Mehedintu et al. J Med Life. .

Abstract

Endometriosis is a debilitating disease with features of chronic inflammation. Endometriosis appears to be one of the most common benign gynecological proliferations in premenopausal women since it is estimated that 10-15% of reproductive aged women suffer from pelvic endometriosis. The biology of endometriosis is unclear. Despite its prevalence, this disease remains poorly understood and current studies prove that there is no relationship between the extent of the disease and its symptomatology. There is no blood test available for the diagnosis of endometriosis. Up to this point, there is no single very successful option for the treatment of endometriosis. Due to the relatively poor efficacy of hormonal therapy for endometriosis, several other experimental therapies are currently undergoing clinical trial.

Keywords: dysmenorrhea; endometriosis; endometriosis therapy; fertility; pain.

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Conflict of interest statement

Disclosures, Funding and Conflicts of Interest: None specified

References

    1. Olive DL. Endometriosis in Clinical Practice. London and New York: Taylor and Francis. 2005
    1. Flores I, Rivera E. Molecular profiling of experimental endometriosis identified gene expression patterns in common with human disease. Fertility and Sterility. 2007;87:1180–1199. - PMC - PubMed
    1. Van Gorp T, Amant F. Endometriosis and the development of malignant tumours of the pelvis. A review of literature. Best Practice and Research. . Clinical Obstetrics and Gynaecology. 2004;18:349–371. - PubMed
    1. Crisan N, Nanu D, compilers. In: Ginecologie. Bucuresti: Ed. Stiinta si tehnica;
    1. Fauconnier A, Chapron C. Relation between pain symptoms and the anatomic location of deep infiltrating endometriosis. Fertil Steril. 2002;78:719–726. - PubMed

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