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Review
. 2014 Sep 15;7(3):373-4.
Epub 2014 Sep 25.

Melatonin and cancer

Affiliations
Review

Melatonin and cancer

A A Zamfir Chiru et al. J Med Life. .

Abstract

Melatonin plays an important role in cancer (tumor growth and metastasis) through different pathways and may have therapeutic significance.

Keywords: cancer; inhibitor; melantonin; receptors; redox processes.

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Conflict of interest statement

Disclosures, Funding and Conflicts of Interest: None specified

References

    1. Slominski A. On the role of melatonin in skin physiology and pathology. Endocrine. 2005;27:137–148. - PMC - PubMed
    1. Cardinali DP. Basic aspects of melatonin action. Sleep Med Rev. 1998;2:175–190. - PubMed
    1. Reppert SM. Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron. 1994;13:1177–1185. - PubMed
    1. Nosjean O. Identification of the melatonin-binding site MT3 as the quinone reductase 2. J Biol Chem. 2000;275:31311–31317. - PubMed
    1. Schuster C. The human MT1 melatonin receptor stimulates cAMP production in the human neuroblastoma cell line SH-SY5Y cells via a calcium-calmodulin signal transduction pathway. J Neuroendocrinol. 2005;17:170–178. - PubMed

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