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. 1989 Apr 11;17(7):2493-502.
doi: 10.1093/nar/17.7.2493.

Kinetics of exchangeable protons in Z DNA: a UV resonance Raman study

A Laigle  1 , L Chinsky, P Y Turpin, B Jollès
Affiliations
Free PMC article

Kinetics of exchangeable protons in Z DNA: a UV resonance Raman study

A Laigle et al. Nucleic Acids Res. .
Free PMC article

Abstract

We have studied the hydrogen-deuterium exchange kinetics of the exchangeable protons of the poly(dG-dC).poly(dG-dC) in the Z form of the polymer, using resonance Raman spectroscopy with 257 nm and 284 nm excitation wavelengths. In our experimental conditions (4.5 M NaCl, phosphate buffer pH7, 2 degrees C) the two amino protons and the imino proton of guanine are exchanged with the same exchange half-time of 13 min, whereas the two amino protons of cytosine are exchanged with the same exchange half-time of 51 min.

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