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Meta-Analysis
. 2014 Sep 26;11 Suppl 3(Suppl 3):S1.
doi: 10.1186/1742-4755-11-S3-S1. Epub 2014 Sep 26.

Preconception care: closing the gap in the continuum of care to accelerate improvements in maternal, newborn and child health

Meta-Analysis

Preconception care: closing the gap in the continuum of care to accelerate improvements in maternal, newborn and child health

Sohni V Dean et al. Reprod Health. .

Abstract

Introduction: Preconception care includes any intervention to optimize a woman's health before pregnancy with the aim to improve maternal, newborn and child health (MNCH) outcomes. Preconception care bridges the gap in the continuum of care, and addresses pre-pregnancy health risks and health problems that could have negative maternal and fetal consequences. It therefore has potential to further reduce global maternal and child mortality and morbidity, especially in low-income countries where the highest burden of pregnancy-related deaths and disability occurs.

Methods: A systematic review and meta-analysis of the evidence was conducted to ascertain the possible impact of preconception care for adolescents, women and couples of reproductive age on MNCH outcomes. A comprehensive strategy was used to search electronic reference libraries, and both observational and clinical controlled trials were included. Cross-referencing and a separate search strategy for each preconception risk and intervention ensured wider study capture.

Results: Women who received preconception care in either a healthcare center or the community showed improved outcomes, such as smoking cessation; increased use of folic acid; breastfeeding; greater odds of obtaining antenatal care; and lower rates of neonatal mortality.

Conclusion: Preconception care is effective in improving pregnancy outcomes. Further studies are needed to evaluate consistency and magnitude of effect in different contexts; develop and assess new preconception interventions; and to establish guidelines for the provision of preconception care.

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Figures

Figure 1
Figure 1
Preconception interventions framework
Figure 2
Figure 2
Preconception community counselling effect on neonatal mortality: evidence from controlled trials
Figure 3
Figure 3
Preconception community counseling effect on breastfeeding: evidence from controlled trials

References

    1. Bhutta ZA, Chopra M, Axelson H, Berman P, Boerma T, Bryce J, Bustreo F, Cavagnero E, Cometto G, Daelmans B. Countdown to 2015 decade report (2000-10): taking stock of maternal, newborn, and child survival. Lancet. 2012;375(9730):2032–2044. - PubMed
    1. Rajaratnam JK, Marcus JR, Flaxman AD, Wang H, Levin-Rector A, Dwyer L, Costa M, Lopez AD, Murray CJL. Neonatal, postneonatal, childhood, and under-5 mortality for 187 countries, 1970-2010: a systematic analysis of progress towards Millennium Development Goal 4. lancet. 2010;375(9730):1988–2008. - PubMed
    1. Kerber KJ, de Graft-Johnson JE, Bhutta ZA, Okong P, Starrs A, Lawn JE. Continuum of care for maternal, newborn, and child health: from slogan to service delivery. Lancet. 2007;370(9595):1358–1369. - PubMed
    1. Atrash H. Preconception care for improving perinatal outcomes: the time to act. Matern Child Health J. 2006;10(suppl 7):3–11. - PMC - PubMed
    1. Centers for Disease Control and Prevention. Recommendations to improve preconception health and health care — United States: a report of the CDC/ATSDR Preconception Care Work Group and the Select Panel on Preconception Care. MMWR. 2006;55 - PubMed