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Comparative Study
. 2014 Nov 22:14:139.
doi: 10.1186/1471-2415-14-139.

Comparison of the Adult Strabismus Quality of Life Questionnaire (AS-20) with the Amblyopia and Strabismus Questionnaire (ASQE) among adults with strabismus who seek medical care in China

Zonghua Wang, Hui Ren, Rosemary Frey, Yang Liu, Deborah Raphael, Wei Bian  1 , Xianyuan Wang
Affiliations
Comparative Study

Comparison of the Adult Strabismus Quality of Life Questionnaire (AS-20) with the Amblyopia and Strabismus Questionnaire (ASQE) among adults with strabismus who seek medical care in China

Zonghua Wang et al. BMC Ophthalmol. .

Abstract

Background: The impact of strabismus on visual function, self-image, self-esteem, and social interactions might decrease health-related quality of life (HRQoL). This study aimed to evaluate the psychometric properties and clinical applications of two strabismus-specific HRQoL questionnaires in the cultural context of China.

Methods: The Chinese versions of the Adult Strabismus Quality of Life Questionnaire (AS-20) and the Amblyopia and Strabismus Questionnaire (ASQE) were self-administered to 304 adults with strabismus. The Cronbach's α coefficient was calculated to assess the internal consistency reliability. The criterion-related validity was identified by exploring Spearman's correlation with the most widely used vision-specific quality of life questionnaire NEI-VFQ-25. One-way ANOVA was employed to examine the differences in the quality of life of strabismus patients with visually normal adults and with other eye diseases patients.

Results: Significantly positive correlations with NEI-VFQ-25 were shown in both scales (r = 0.21 - 0.44, p <0.05, p <0.01). Both scales could distinguish individuals with strabismus from visually normal adults (p <0.001) and adults with other eye diseases (p <0.001). The overall Cronbach's α value were 0.91 for the AS-20 and 0.89 for the ASQE; and for the subscales, the α value ranged from 0.68 to 0.90.

Conclusion: This was the first cross-sectional study to compare the psychometric properties of two strabismus-targeted questionnaires, AS-20 and ASQE in the context of Chinese culture. Both AS-20 and ASQE showed satisfactory and comparable properties for measuring HRQoL in strabismus patients.

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Figures

Figure 1
Figure 1
The effects of strabismus on HRQoL in patients with and without amblyopia/diplopia. This figure was derived from Independent t- test (*p <.05, 2-tailed, **p <.01, 2-tailed), aiming to interpret the effects of strabismus on quality of life in patients with and without amblyopia/diplopia.
Figure 2
Figure 2
Comparison of mean of strabismic adults versus visually normal adults and patients with other eye diseases. A. the overall ASQE. B. fear of losing better eye. C. distance estimation. D. disorientation. E. diplopia. F. contact & cosmetic G. the overall AS-20. H. psychosocial. I. function. This histogram was derived from one-way ANOVA and Tukey's Multiple Comparison Test (**P <.001, 2-tailed), aiming to interpret the comparisons of average health-related quality of life scores among visually normal adults, adult patients with strabismus and adults with other eye diseases. NA, normal adults; AS, adults with strabismus; AOED, adults with other eye diseases.
See this image and copyright information in PMC

References

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Pre-publication history
    1. The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2415/14/139/prepub

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