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Review
. 2014;34(5):571-6.
doi: 10.1016/j.semnephrol.2014.08.011.

Pathophysiology of resistant hypertension in chronic kidney disease

Vito M Campese  1
Affiliations
Review

Pathophysiology of resistant hypertension in chronic kidney disease

Vito M Campese. Semin Nephrol. 2014.

Abstract

Hypertension associated with chronic kidney diseases often is resistant to drug treatment. This review deals with two main aspects of the management of CKD patients with hypertension: the role of sodium/volume and the need for dietary salt restriction, as well as appropriate use of diuretics and what currently is called sequential nephron blockade; the second aspect that is addressed extensively in this review is the role of the sympathetic nervous system and the possible clinical use of renal denervation.

Keywords: Hypertension; chronic kidney disease; renal denervation; sodium intake; sympathetic nervous system.

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