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. 2014 Nov 20;19(11):19220-42.
doi: 10.3390/molecules191119220.

Volatile profiling of aromatic traditional medicinal plant, Polygonum minus in different tissues and its biological activities

Rafidah Ahmad  1 , Syarul Nataqain Baharum  2 , Hamidun Bunawan  3 , Minki Lee  4 , Normah Mohd Noor  5 , Emelda Roseleena Rohani  6 , Norashikin Ilias  7 , Noraziah Mohamad Zin  8
Affiliations

Volatile profiling of aromatic traditional medicinal plant, Polygonum minus in different tissues and its biological activities

Rafidah Ahmad et al. Molecules. .

Abstract

The aim of this research was to identify the volatile metabolites produced in different organs (leaves, stem and roots) of Polygonum minus, an important essential oil producing crop in Malaysia. Two methods of extraction have been applied: Solid Phase Microextraction (SPME) and hydrodistillation coupled with Gas Chromatography-Mass Spectrometry (GC-MS). Approximately, 77 metabolites have been identified and aliphatic compounds contribute significantly towards the aroma and flavour of this plant. Two main aliphatic compounds: decanal and dodecanal were found to be the major contributor. Terpenoid metabolites were identified abundantly in leaves but not in the stem and root of this plant. Further studies on antioxidant, total phenolic content, anticholinesterase and antimicrobial activities were determined in the essential oil and five different extracts. The plant showed the highest DPPH radical scavenging activity in polar (ethanol) extract for all the tissues tested. For anti-acetylcholinesterase activity, leaf in aqueous extract and methanol extract showed the best acetylcholinesterase inhibitory activities. However, in microbial activity, the non-polar extracts (n-hexane) showed high antimicrobial activity against Methicillin-resistant Staphylococcus aureus (MRSA) compared to polar extracts. This study could provide the first step in the phytochemical profiles of volatile compounds and explore the additional value of pharmacology properties of this essential oil producing crop Polygonum minus.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Score plot of (a) and PCA loading (b) of volatile compounds in P. minus in different tissues by GC-MS. Leaf (●), stem (■) and root (▲) using SPME.
Figure 2
Figure 2
Score plot of (a) and PCA loading (b) of essential oil in P. minus in different tissues. Leaf (●), stem (■) and root (▲).
Figure 3
Figure 3
Number of compounds found by the SPME technique and the hydrodistillation technique.
See this image and copyright information in PMC

References

    1. Hassan W.W. Healing Herbs of Malaysia. Federal Land Development Authority (FELDA); Kuala Lumpur, Malaysia: 2007.
    1. Hunter M. Australian kesom oil—A new essential oil for the flavour and fragrance industry. Agro Food Ind. Hi Tech. 1996;7:26–28.
    1. Zakaria M., Mohad M.A. Traditional Malay Medicinal Plants. ITNM; Kuala Lumpur, Malaysia: 2010.
    1. George A., Chinnappan S., Chintamaneni M., Kotak C.V., Choudhary Y., Kueper T., Radhakrishnan A. Anti-inflammatory effects of Polygonum minus (Huds) extract (LineminusTM) in in vitro enzyme assays and carrageenan induced paw edema. BMC Complement. Altern. Med. 2014;14:355. doi: 10.1186/1472-6882-14-355. - DOI - PMC - PubMed
    1. Haris H.H., Ming Y.K., Perin F., Blanche C., Jinapong N. Split-face placebo controlled evaluation of the in vivo anti-ageing efficacy of lineminus™ cream (Polygonum minus extract) in healthy asian skin type female subjects. Asian J. Pharm. Clin. Res. 2014;7:7–13.

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