Reply: Heterogeneity of intermediate-stage HCC necessitates personalized management including surgery

Alejandro Forner¹, Marine Gilabert², Jordi Bruix¹, Jean-Luc Raoul²

Affiliations

¹ Barcelona Clinic Liver Cancer (BCLC) Group, Liver Unit, Networked Biomedical Research Centre for Hepatic and Digestive Diseases (CIBERehd), Hospital Clinic Barcelona, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), University of Barcelona, Carrer Villarroel 170, 08036 Barcelona, Spain.
² Department of Medical Oncology, Institut Paoli-Calmettes, 232 Boulevard de Sainte Marguerite, 13009 Marseille, France.

PMID: 25421282
DOI: 10.1038/nrclinonc.2014.122-c2

Comment

Reply: Heterogeneity of intermediate-stage HCC necessitates personalized management including surgery

Alejandro Forner et al. Nat Rev Clin Oncol. 2015 Jan.

. 2015 Jan;12(1):10.

doi: 10.1038/nrclinonc.2014.122-c2. Epub 2014 Nov 25.

Authors

Alejandro Forner¹, Marine Gilabert², Jordi Bruix¹, Jean-Luc Raoul²

Affiliations

¹ Barcelona Clinic Liver Cancer (BCLC) Group, Liver Unit, Networked Biomedical Research Centre for Hepatic and Digestive Diseases (CIBERehd), Hospital Clinic Barcelona, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), University of Barcelona, Carrer Villarroel 170, 08036 Barcelona, Spain.
² Department of Medical Oncology, Institut Paoli-Calmettes, 232 Boulevard de Sainte Marguerite, 13009 Marseille, France.

PMID: 25421282
DOI: 10.1038/nrclinonc.2014.122-c2

No abstract available

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Comment on

Treatment of intermediate-stage hepatocellular carcinoma.
Forner A, Gilabert M, Bruix J, Raoul JL. Forner A, et al. Nat Rev Clin Oncol. 2014 Sep;11(9):525-35. doi: 10.1038/nrclinonc.2014.122. Epub 2014 Aug 5. Nat Rev Clin Oncol. 2014. PMID: 25091611 Review.
Heterogeneity of intermediate-stage HCC necessitates personalized management including surgery.
Gao Q, Wang XY, Zhou J, Fan J. Gao Q, et al. Nat Rev Clin Oncol. 2015 Jan;12(1):10. doi: 10.1038/nrclinonc.2014.122-c1. Epub 2014 Nov 25. Nat Rev Clin Oncol. 2015. PMID: 25421283 No abstract available.

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References

1. Hepatology. 2011 Mar;53(3):1020-2 - PubMed
1. Gastroenterology. 2014 Jun;146(7):1599-602 - PubMed
1. Lancet. 2012 Mar 31;379(9822):1245-55 - PubMed
1. Semin Liver Dis. 1999;19(3):329-38 - PubMed
1. Cardiovasc Intervent Radiol. 2010 Feb;33(1):41-52 - PubMed

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Reply: Heterogeneity of intermediate-stage HCC necessitates personalized management including surgery

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