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. 1989 Apr;27(4):651-3.
doi: 10.1128/jcm.27.4.651-653.1989.

Seroepidemiology of human herpesvirus 6 infection in normal children and adults

T Okuno  1 , K Takahashi, K Balachandra, K Shiraki, K Yamanishi, M Takahashi, K Baba
Affiliations

Seroepidemiology of human herpesvirus 6 infection in normal children and adults

T Okuno et al. J Clin Microbiol. 1989 Apr.

Abstract

Sera from normal subjects were examined for reactivity to human herpesvirus 6 (HHV-6) by the anticomplement immunofluorescence test. Of a total of 179 serum specimens from donors aged from under 10 to 59 years, 141 specimens showed positive reactivity against HHV-6. The positive rate was 70 to 83% for all age groups, and there were no substantial differences in the positive rates. Sera from younger children aged from 0 to 21 months were then examined in detail. The antibody-positive rate of children aged from 0 to 5 months decreased from 52 to 5%, but it gradually increased by 12 months. Almost all children had the antibody against this virus after 13 months of age.

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