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Review
. 2015 Jul;100(4):F350-4.
doi: 10.1136/archdischild-2014-306193. Epub 2014 Nov 25.

Early onset neonatal sepsis: diagnostic dilemmas and practical management

A R Bedford Russell  1 , R Kumar  1
Affiliations
Review

Early onset neonatal sepsis: diagnostic dilemmas and practical management

A R Bedford Russell et al. Arch Dis Child Fetal Neonatal Ed. 2015 Jul.

Abstract

Early onset neonatal sepsis is persistently associated with poor outcomes, and incites clinical practice based on the fear of missing a treatable infection in a timely fashion. Unnecessary exposure to antibiotics is also hazardous. Diagnostic dilemmas are discussed in this review, and suggestions offered for practical management while awaiting a more rapidly available 'gold standard' test; in an ideal world, this test would be 100% sensitive and 100% specific for the presence of organisms.

Keywords: Evidence Based Medicine; Immunology; Infectious Diseases; Microbiology; Neonatology.

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