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Review
. 2014;6(10):1113-26.
doi: 10.2217/imt.14.67.

An update on the use of immunoglobulin for the treatment of immunodeficiency disorders

Stephanie Albin  1 , Charlotte Cunningham-Rundles
Affiliations
Review

An update on the use of immunoglobulin for the treatment of immunodeficiency disorders

Stephanie Albin et al. Immunotherapy. 2014.

Abstract

For patients with significant antibody deficiencies, immunoglobulin therapy is the mainstay of treatment as it significantly reduces both the frequency and severity of infections. The formulations and delivery methods of immunoglobulin have evolved over time, and continued improvements have allowed for increased access to this effective medication. This review is an update on the current status of immunoglobulin therapy in immunodeficiency disorders, and discusses the mechanisms, forms and dosing, and indications for immunoglobulin replacement.

Keywords: antibody deficiency; immunoglobulin replacement; intravenous immunoglobulin; mechanisms of immunoglobulin; primary immunodeficiency; subcutaneous immunoglobulin.

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