doi: 10.1007/BF00332232.
The bI4 RNA mitochondrial maturase of Saccharomyces cerevisiae can stimulate intra-chromosomal recombination in Escherichia coli
Affiliations
- PMID: 2543908
- DOI: 10.1007/BF00332232
Item in Clipboard
The bI4 RNA mitochondrial maturase of Saccharomyces cerevisiae can stimulate intra-chromosomal recombination in Escherichia coli
Mol Gen Genet.
1989 Mar.
Abstract
When the bI4 RNA maturase, encoded by the fourth intron of the mitochondrial cytochrome b gene of Saccharomyces cerevisiae, was expressed in Escherichia coli, formation of intra-chromosomal Lac+ recombinants was stimulated threefold. This "hyper-rec" phenotype was recA as well as recBCD dependent. The most active form of the bI4 maturase stimulated homologous recombination whereas splicing deficient mutants of bI4 maturase were either deficient in or unable to stimulate homologous recombination.
Similar articles
-
Synthesis and function of the mitochondrial intron--encoded bI4 RNA maturase from Saccharomyces cerevisiae. Effects of upstream frame-shift mutations.Curr Genet. 1989 Oct;16(4):241-6. doi: 10.1007/BF00422109. Curr Genet. 1989. PMID: 2560681
-
Connections between RNA splicing and DNA intron mobility in yeast mitochondria: RNA maturase and DNA endonuclease switching experiments.Mol Cell Biol. 1992 Feb;12(2):696-705. doi: 10.1128/mcb.12.2.696-705.1992. Mol Cell Biol. 1992. PMID: 1310149 Free PMC article.
-
The mitochondrial genome of Schizosaccharomyces pombe. Stimulation of intra-chromosomal recombination in Escherichia coli by the gene product of the first cox1 intron.Curr Genet. 1991 Apr;19(4):295-9. doi: 10.1007/BF00355058. Curr Genet. 1991. PMID: 1651177
-
Site-specific recombinases: changing partners and doing the twist.J Bacteriol. 1986 Feb;165(2):341-7. doi: 10.1128/jb.165.2.341-347.1986. J Bacteriol. 1986. PMID: 3003022 Free PMC article. Review. No abstract available.
-
Two for the price of one: a bifunctional intron-encoded DNA endonuclease-RNA maturase.Genes Dev. 2003 Dec 1;17(23):2860-3. doi: 10.1101/gad.1162503. Genes Dev. 2003. PMID: 14665667 Review. No abstract available.
Cited by
-
Genetic approaches to the study of mitochondrial biogenesis in yeast.Antonie Van Leeuwenhoek. 1992 Aug;62(1-2):131-53. doi: 10.1007/BF00584467. Antonie Van Leeuwenhoek. 1992. PMID: 1444332 Review.
-
Synthesis and function of the mitochondrial intron--encoded bI4 RNA maturase from Saccharomyces cerevisiae. Effects of upstream frame-shift mutations.Curr Genet. 1989 Oct;16(4):241-6. doi: 10.1007/BF00422109. Curr Genet. 1989. PMID: 2560681
-
Mutations in the mitochondrial split gene COXI are preferentially located in exons: a mapping study of 170 mutants.Mol Gen Genet. 1995 Feb 20;246(4):445-54. doi: 10.1007/BF00290448. Mol Gen Genet. 1995. PMID: 7891658
-
The biology of yeast mitochondrial introns.Mol Biol Rep. 1993 Jun;18(1):1-13. doi: 10.1007/BF01006890. Mol Biol Rep. 1993. PMID: 8232290 Review. No abstract available.
-
Connections between RNA splicing and DNA intron mobility in yeast mitochondria: RNA maturase and DNA endonuclease switching experiments.Mol Cell Biol. 1992 Feb;12(2):696-705. doi: 10.1128/mcb.12.2.696-705.1992. Mol Cell Biol. 1992. PMID: 1310149 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
