Considering prior plausibility in clinical trials does not mean ignoring scientific evidence

Affiliations

¹ Michael and Marian Illitch Department of Surgery, Wayne State University School of Medicine, 3990 John R St., Detroit, MI 48201, USA; Molecular Therapeutics Program, Wayne State University, Barbara Ann Karmanos Cancer Institute, 4100 John R St., Detroit, MI 48201, USA. Electronic address: gorskid@med.wayne.edu.
² Department of Neurology, Yale University, 40 Temple St., Suite 6C, New Haven CT 06510, USA.

Comment

David H Gorski et al. Trends Mol Med. 2014 Nov.

. 2014 Nov;20(11):600-1.

doi: 10.1016/j.molmed.2014.10.001. Epub 2014 Oct 17.

¹ Michael and Marian Illitch Department of Surgery, Wayne State University School of Medicine, 3990 John R St., Detroit, MI 48201, USA; Molecular Therapeutics Program, Wayne State University, Barbara Ann Karmanos Cancer Institute, 4100 John R St., Detroit, MI 48201, USA. Electronic address: gorskid@med.wayne.edu.
² Department of Neurology, Yale University, 40 Temple St., Suite 6C, New Haven CT 06510, USA.

No abstract available

Keywords: clinical trials; complementary and alternative medicine; evidence-based medicine; integrative medicine; science-based medicine.

Comment on

Clinical trials of integrative medicine: testing whether magic works?
Gorski DH, Novella SP. Gorski DH, et al. Trends Mol Med. 2014 Sep;20(9):473-6. doi: 10.1016/j.molmed.2014.06.007. Epub 2014 Aug 20. Trends Mol Med. 2014. PMID: 25150944
Making sense of prior probabilities in research.
Rutten LA, Mathie RT, Manchanda RK. Rutten LA, et al. Trends Mol Med. 2014 Nov;20(11):599-600. doi: 10.1016/j.molmed.2014.09.007. Epub 2014 Oct 29. Trends Mol Med. 2014. PMID: 25362626 No abstract available.