Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Jan;24(1):1-17.
doi: 10.1016/j.soc.2014.09.001. Epub 2014 Oct 3.

Epidemiology of hepatocellular carcinoma

Kelly J Lafaro  1 , Aram N Demirjian  2 , Timothy M Pawlik  3
Affiliations
Review

Epidemiology of hepatocellular carcinoma

Kelly J Lafaro et al. Surg Oncol Clin N Am. 2015 Jan.

Abstract

Hepatocellular carcinoma (HCC) is the most common histologic type of primary liver cancer, accounting for between 85% and 90% of these malignancies. The overall prognosis of patients with liver cancer is poor, and an understanding of this disease and its risk factors is crucial for screening at-risk individuals, early recognition, and timely diagnosis. Most HCCs arise in the background of chronic liver disease caused by hepatitis B virus, hepatitis C virus, and chronic excessive alcohol intake. These underlying causes are characterized by marked variations in geography, gender, and other well-documented risk factors, some of which are potentially preventable.

Keywords: Aflatoxin; Chronic liver disease; Cirrhosis; Hepatitis B; Hepatitis C; Hepatocellular carcinoma; Incidence; Risk factors.

PubMed Disclaimer