Lanthiopeptin, a new peptide antibiotic. Production, isolation and properties of lanthiopeptin
- PMID: 2544544
- DOI: 10.7164/antibiotics.42.837
Lanthiopeptin, a new peptide antibiotic. Production, isolation and properties of lanthiopeptin
Abstract
A strain of Streptoverticillium cinnamoneum produced a peptide antibiotic named lanthiopeptin, which contained four unusual amino acids, erythro-beta-hydroxyaspartic acid, mesolanthionine, threo-beta-methyllanthionine and lysinoalanine. Lanthiopeptin showed antiviral activity against herpes simplex virus type 1 KOS strain infection in Vero cells by cytopathic effect reduction assay. The structure of lanthiopeptin is similar to that of ancovenin.
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