Fontan circulation: the search for targeted therapy

Affiliations

¹ From the Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA; and Department of Pediatrics, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA.
² From the Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA; and Department of Pediatrics, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA. paridon@email.chop.edu.

Editorial

David J Goldberg et al. Circulation. 2014.

. 2014 Dec 2;130(23):1999-2001.

doi: 10.1161/CIRCULATIONAHA.114.013365. Epub 2014 Oct 20.

¹ From the Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA; and Department of Pediatrics, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA.
² From the Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA; and Department of Pediatrics, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA. paridon@email.chop.edu.

No abstract available

Keywords: Editorials; Fontan procedure; exercise; pulmonary hypertension.

Comment on

Bosentan improves exercise capacity in adolescents and adults after Fontan operation: the TEMPO (Treatment With Endothelin Receptor Antagonist in Fontan Patients, a Randomized, Placebo-Controlled, Double-Blind Study Measuring Peak Oxygen Consumption) study.
Hebert A, Mikkelsen UR, Thilen U, Idorn L, Jensen AS, Nagy E, Hanseus K, Sørensen KE, Søndergaard L. Hebert A, et al. Circulation. 2014 Dec 2;130(23):2021-30. doi: 10.1161/CIRCULATIONAHA.113.008441. Epub 2014 Oct 20. Circulation. 2014. PMID: 25446057 Clinical Trial.