Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Mar:82-83:137-44.
doi: 10.1016/j.addr.2014.11.012. Epub 2014 Nov 14.

Stem cell treatment of erectile dysfunction

Amjad Alwaal  1 , Uwais B Zaid  2 , Ching-Shwun Lin  2 , Tom F Lue  2
Affiliations
Review

Stem cell treatment of erectile dysfunction

Amjad Alwaal et al. Adv Drug Deliv Rev. 2015 Mar.

Abstract

Erectile Dysfunction (ED) is a common disease that typically affects older men. While oral type-5 phosphodieserase inhibitors (PDE5Is) represent a successful first-line therapy, many patients do not respond to this treatment leading researchers to look for alternative treatment modalities. Stem cell (SC) therapy is a promising new frontier for the treatment of those patients and many studies demonstrated its therapeutic effects. In this article, using a Medline database search of all relevant articles, we present a summary of the scientific principles behind SCs and their use for treatment of ED. We discuss specifically the different types of SCs used in ED, the methods of delivery tested, and the methods attempted to enhance SC therapy effect. In addition, we review the current preclinical literature on SC therapy for ED and present a summary of its findings in addition to the single clinical trial published.

Keywords: Erectile dysfunction; Stem cell therapy.

PubMed Disclaimer