Cross-colonization of infants with probiotic organisms in a neonatal unit

L Hickey¹, S M Garland², S E Jacobs³, C P F O'Donnell⁴, S N Tabrizi²; ProPrems Study Group

Collaborators, Affiliations

Collaborators

ProPrems Study Group:
S M Garland, S E Jacobs, J M Tobin, S N Tabrizi, M Pirotta, S Donath, G F Opie, M L K Tang, C J Morley, S Donath, L Hickey, K Tan, A Lewis, A Veldman, J Travadi, I M R Wright, D A Osborn, J Sinn, J Levison, J A Stack, A G DePaoli, N C Austin, B A Darlow, J M Alsweiler, M J Buksh

Affiliations

¹ Department of Neonatal Medicine, Royal Children's Hospital, Parkville, Victoria, Australia; School of Medicine & Medical Science, University College Dublin, Ireland; Neonatal Services, Royal Women's Hospital, Parkville, Victoria, Australia. Electronic address: leah.hickey@rch.org.au.
² The Women's Centre for Infectious Diseases, The Royal Women's Hospital, Parkville, Victoria, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria, Australia; Department of Microbiology, Royal Children's Hospital, Parkville, Victoria, Australia; Infection and Immunity Group, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.
³ Neonatal Services, Royal Women's Hospital, Parkville, Victoria, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria, Australia; Infection and Immunity Group, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia; Neonatal Research Group, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.
⁴ School of Medicine & Medical Science, University College Dublin, Ireland; The National Maternity Hospital, Holles Street, Dublin, Ireland.

PMID: 25447201
DOI: 10.1016/j.jhin.2014.09.006

Randomized Controlled Trial

Cross-colonization of infants with probiotic organisms in a neonatal unit

L Hickey et al. J Hosp Infect. 2014 Dec.

. 2014 Dec;88(4):226-9.

doi: 10.1016/j.jhin.2014.09.006. Epub 2014 Oct 2.

Authors

L Hickey¹, S M Garland², S E Jacobs³, C P F O'Donnell⁴, S N Tabrizi²; ProPrems Study Group

Collaborators

ProPrems Study Group:
S M Garland, S E Jacobs, J M Tobin, S N Tabrizi, M Pirotta, S Donath, G F Opie, M L K Tang, C J Morley, S Donath, L Hickey, K Tan, A Lewis, A Veldman, J Travadi, I M R Wright, D A Osborn, J Sinn, J Levison, J A Stack, A G DePaoli, N C Austin, B A Darlow, J M Alsweiler, M J Buksh

Affiliations

¹ Department of Neonatal Medicine, Royal Children's Hospital, Parkville, Victoria, Australia; School of Medicine & Medical Science, University College Dublin, Ireland; Neonatal Services, Royal Women's Hospital, Parkville, Victoria, Australia. Electronic address: leah.hickey@rch.org.au.
² The Women's Centre for Infectious Diseases, The Royal Women's Hospital, Parkville, Victoria, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria, Australia; Department of Microbiology, Royal Children's Hospital, Parkville, Victoria, Australia; Infection and Immunity Group, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.
³ Neonatal Services, Royal Women's Hospital, Parkville, Victoria, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria, Australia; Infection and Immunity Group, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia; Neonatal Research Group, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.
⁴ School of Medicine & Medical Science, University College Dublin, Ireland; The National Maternity Hospital, Holles Street, Dublin, Ireland.

PMID: 25447201
DOI: 10.1016/j.jhin.2014.09.006

Abstract

This study aimed to assess probiotic cross-colonization between infants in a neonatal unit where probiotics were being administered to preterm infants during a clinical trial. We tested stool samples from all infants present in the unit at two time points; the first was during the trial and the second was after trial completion. Samples from 43 infants were tested during the trial; all five infants receiving probiotics and three of 38 not receiving probiotics were colonized. Only one of 44 infants tested after the trial was colonized. The rate of cross-colonization was lower than in previous probiotic studies.

Keywords: Cross-colonization; Neonatal unit; Preterm infants; Probiotics.

PubMed Disclaimer

Publication types

Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- ClinicalKey
- Elsevier Science
Other Literature Sources
- scite Smart Citations
Medical
- MedlinePlus Health Information

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Cross-colonization of infants with probiotic organisms in a neonatal unit

Collaborators

Affiliations

Cross-colonization of infants with probiotic organisms in a neonatal unit

Authors

Collaborators

Affiliations

Abstract

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical