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. 1989 May 29;488(1-2):387-9.
doi: 10.1016/0006-8993(89)90736-1.

Chronic septal lesions cause upregulation of cholinergic but not noradrenergic hippocampal phosphoinositide hydrolysis

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Chronic septal lesions cause upregulation of cholinergic but not noradrenergic hippocampal phosphoinositide hydrolysis

D J Connor et al. Brain Res. .

Abstract

The functional integrity of hippocampal muscarinic and noradrenergic receptors was assessed utilizing phosphatidyl inositol (PI) hydrolysis. Four months following septal lesions an enhanced hippocampal PI response to carbachol stimulation (61%) was observed while no effect was found in maximal noradrenergic stimulation.

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