Chronic septal lesions cause upregulation of cholinergic but not noradrenergic hippocampal phosphoinositide hydrolysis
- PMID: 2545306
- DOI: 10.1016/0006-8993(89)90736-1
Chronic septal lesions cause upregulation of cholinergic but not noradrenergic hippocampal phosphoinositide hydrolysis
Abstract
The functional integrity of hippocampal muscarinic and noradrenergic receptors was assessed utilizing phosphatidyl inositol (PI) hydrolysis. Four months following septal lesions an enhanced hippocampal PI response to carbachol stimulation (61%) was observed while no effect was found in maximal noradrenergic stimulation.
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