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Review
. 2015 Feb;31(1):139-47, ix.
doi: 10.1016/j.cger.2014.08.023. Epub 2014 Oct 18.

Obstructive sleep apnea and type 2 diabetes in older adults

Karoline Moon  1 , Naresh M Punjabi  1 , R Nisha Aurora  2
Affiliations
Review

Obstructive sleep apnea and type 2 diabetes in older adults

Karoline Moon et al. Clin Geriatr Med. 2015 Feb.

Abstract

Both obstructive sleep apnea (OSA) and type 2 diabetes mellitus are commonly seen in older adults. Over the last decade, there has been increasing recognition that OSA is highly prevalent in persons with type 2 diabetes and related metabolic conditions such as insulin resistance and glucose intolerance. Intermittent hypoxemia and recurrent arousals in OSA trigger a repertoire of pathophysiological events, which can in turn alter glucose homeostasis and possibly increase the risk for type 2 diabetes. Conversely, there is evidence that type 2 diabetes may alter the progression and expression of sleep-disordered breathing.

Keywords: Aging; Central sleep apnea; Obstructive sleep apnea; Type 2 diabetes.

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Figures

Figure 1
Figure 1
Prevalence of obstructive sleep as a function of age.
Figure 2
Figure 2
Associations and causal links OSA and metabolic abnormalities.
Figure 3
Figure 3
Interactions between age, obstructive sleep apnea, and type 2 diabetes
See this image and copyright information in PMC

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