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Review
. 2015 Feb;31(1):139-47, ix.
doi: 10.1016/j.cger.2014.08.023. Epub 2014 Oct 18.

Obstructive sleep apnea and type 2 diabetes in older adults

Karoline Moon  1 , Naresh M Punjabi  1 , R Nisha Aurora  2
Affiliations
Review

Obstructive sleep apnea and type 2 diabetes in older adults

Karoline Moon et al. Clin Geriatr Med. 2015 Feb.

Abstract

Both obstructive sleep apnea (OSA) and type 2 diabetes mellitus are commonly seen in older adults. Over the last decade, there has been increasing recognition that OSA is highly prevalent in persons with type 2 diabetes and related metabolic conditions such as insulin resistance and glucose intolerance. Intermittent hypoxemia and recurrent arousals in OSA trigger a repertoire of pathophysiological events, which can in turn alter glucose homeostasis and possibly increase the risk for type 2 diabetes. Conversely, there is evidence that type 2 diabetes may alter the progression and expression of sleep-disordered breathing.

Keywords: Aging; Central sleep apnea; Obstructive sleep apnea; Type 2 diabetes.

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Figures

Figure 1
Figure 1
Prevalence of obstructive sleep as a function of age.
Figure 2
Figure 2
Associations and causal links OSA and metabolic abnormalities.
Figure 3
Figure 3
Interactions between age, obstructive sleep apnea, and type 2 diabetes
See this image and copyright information in PMC

References

    1. U.S. Department of Health and Human Services. Wake up America: A National Sleep Alert. Bethesda, MD: 1993.
    1. Vaessen TJ, Overeem S, Sitskoorn MM. Cognitive complaints in obstructive sleep apnea. Sleep Med Rev. 2014 - PubMed
    1. Konecny T, Kara T, Somers VK. Obstructive sleep apnea and hypertension: an update. Hypertension. 2014;63(2):203–209. - PMC - PubMed
    1. Kasai T, Floras JS, Bradley TD. Sleep apnea and cardiovascular disease: a bidirectional relationship. Circulation. 2012;126(12):1495–1510. - PubMed
    1. Iftikhar IH, Khan MF, Das A, et al. Meta-analysis: continuous positive airway pressure improves insulin resistance in patients with sleep apnea without diabetes. Ann Am Thorac Soc. 2013;10(2):115–120. - PMC - PubMed

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