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Review
. 2014 Dec;28(4):563-83.
doi: 10.1016/j.idc.2014.08.001. Epub 2014 Nov 20.

Pre-exposure prophylaxis for human immunodeficiency virus: the past, present, and future

Amanda D Castel  1 , Manya Magnus  2 , Alan E Greenberg  2
Affiliations
Review

Pre-exposure prophylaxis for human immunodeficiency virus: the past, present, and future

Amanda D Castel et al. Infect Dis Clin North Am. 2014 Dec.

Abstract

This article presents an overview of pre-exposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) prevention. The authors describe the past animal and human research that has been conducted that informs our current understanding of PrEP; summarize ongoing research in the area, including describing new regimens and delivery mechanisms being studied for PrEP; and highlight key issues that must be addressed in order to implement and optimize the use of this HIV prevention tool.

Keywords: Adherence; Biomedical intervention; HIV prevention; Implementation; Pre-exposure prophylaxis.

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