Controversies concerning mitochondrial replacement therapy

Affiliations

¹ Masters of Bioethics Program, Columbia University, New York, New York.
² Department of Psychiatry, University of Oxford, Oxford, United Kingdom.
³ Department of Obstetrics and Gynecology and Center for Women's Reproductive Care, Columbia University, New York, New York.

Review

Robert Klitzman et al. Fertil Steril. 2015 Feb.

. 2015 Feb;103(2):344-6.

doi: 10.1016/j.fertnstert.2014.10.028. Epub 2014 Nov 20.

¹ Masters of Bioethics Program, Columbia University, New York, New York.
² Department of Psychiatry, University of Oxford, Oxford, United Kingdom.
³ Department of Obstetrics and Gynecology and Center for Women's Reproductive Care, Columbia University, New York, New York.

No abstract available

References

1. Department of Health, UK. [September 24, 2014];Mitochondrial donation: a consultation on draft regulations to permit the use of new treatment techniques to prevent the transmission of a serious mitochondrial disease from mother to child. 2014 Feb; Available at: https://www.gov.uk/government/uploads/system/uploads/attachment_data/fil....
1. Reinhardt K, Dowling DK, Morrow EH. Policy forum: mitochondrial replacement, evolution, and the clinic. Science. 2013;341:1345–6. - PubMed
1. Chinnery PF, Craven L, Mitalipov S, Stewart JB, Herbert M, Turnbull DM. The challenges of mitochondrial replacement. PLoS Genet. 2014;10:e1004315. - PMC - PubMed
1. Beekman M, Dowling DK, Aanen DK. The costs of being male: are there sex-specific effects of uniparental mitochondrial inheritance? Philos Trans R Soc Lond B Biol Sci. 2014;369:20130440. - PMC - PubMed
1. Zoon KC. [September 24, 2014];Letter to sponsors/researchers: Human cells used in therapy involving the transfer of genetic material by means other than the union of gamete nuclei. Available at: http://www.fda.gov/BiologicsBloodVaccines/SafetyAvailability/ucm105852.htm.