A longer life for yeast with good memory
- PMID: 25458008
- DOI: 10.1016/j.devcel.2014.11.011
A longer life for yeast with good memory
Abstract
Cell polarity establishment has been studied in great detail, but much less is known about mechanisms that prevent polarization. Reporting recently in Cell, Meitinger et al. (2014) identify an elaborate mechanism in yeast cells that efficiently inhibits Cdc42 activation in cytokinesis remnants. Failure of this "anti-polarization" memory increases replicative aging.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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A memory system of negative polarity cues prevents replicative aging.Cell. 2014 Nov 20;159(5):1056-1069. doi: 10.1016/j.cell.2014.10.014. Epub 2014 Nov 13. Cell. 2014. PMID: 25416945
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