Comparative effectiveness and practice variation in neonatal care

Abstract

Comparative effectiveness research (CER) is a relatively new term for clinical research that directly assists patients, clinicians, and policymakers in making informed decisions to improve health care. In neonatology, there are similarities and differences between CER and existing clinical research and quality improvement literature. This article uses existing examples in neonatal literature to describe CER methodology and list some future directions and challenges in neonatal CER.

Keywords: Clinical research methods; Comparative effectiveness; Neonatology.