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Comment
. 2014 Dec;22(12):660-2.
doi: 10.1016/j.tim.2014.10.006. Epub 2014 Nov 4.

Can chatter between microbes prevent cholera?

Jessica A Thompson  1 , Rita Almeida Oliveira  1 , Karina B Xavier  2
Affiliations
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Can chatter between microbes prevent cholera?

Jessica A Thompson et al. Trends Microbiol. 2014 Dec.

Abstract

Tackling the global rise in antibiotic resistance requires new therapies against infectious microbes. A recent microbiome study identified commensal gut bacteria that reduce colonisation by the cholera pathogen, Vibrio cholerae. This antagonistic interaction might be mediated by quorum sensing, suggesting that these natural microbe-microbe interactions can help prevent infectious disease.

Keywords: AI-2; LuxS; bacterial signalling; cell–cell communication; microbiota; quorum sensing.

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