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. 2014 Dec:14 Suppl 6:s50-5.
doi: 10.7861/clinmedicine.14-6-s50.

Rheumatoid arthritis: from palliation to remission in two decades

Philip M Brown  1 , John D Isaacs  2
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Free article

Rheumatoid arthritis: from palliation to remission in two decades

Philip M Brown et al. Clin Med (Lond). 2014 Dec.
Free article

Abstract

The last 20 years have seen a transformation in the landscape of rheumatoid arthritis, which has changed from being a life limiting condition to a chronic but often remitting illness. The importance of early disease control, the better use of existing therapies, and the development of new therapies have all been key to this success. The future of therapy now lies in the identification of stratifying biomarkers, to allow more rational delivery of treatment. The ultimate goal remains the reintroduction of immune tolerance to potentially achieve a 'cure.'

Keywords: Rheumatoid arthritis; biologics; biomarkers; immune tolerance; stratified medicine.

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