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. 2014 Nov;77(5):227-9.
doi: 10.4046/trd.2014.77.5.227. Epub 2014 Nov 28.

A Case of Segniliparus rugosus Pulmonary Infection in an Immunocompetent Patient with Non-cystic Fibrosis

Jung Yeon Lee  1 , Gyu Rak Chon  1 , Tae-Young Jung  2 , Heungsup Sung  3 , Tae Sun Shim  4 , Kyung-Wook Jo  4
Affiliations

A Case of Segniliparus rugosus Pulmonary Infection in an Immunocompetent Patient with Non-cystic Fibrosis

Jung Yeon Lee et al. Tuberc Respir Dis (Seoul). 2014 Nov.

Abstract

Segniliparus species is a novel genus that is reported to be the new emerging respiratory pathogens. Here, we report a very rare case of S. rugosus pulmonary infection in an immunocompetent patient with non-cystic fibrosis. The organism was identified by 16S rRNA gene sequencing. The patient was successfully treated with antibiotics.

Keywords: Nontuberculous Mycobacteria; RNA Sequencing; Respiratory Tract Infections.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1
An initial chest computed tomography scan of the studied patient showing bronchiectatic changes with small centrilobular nodules in the lingular division of the left upper lobe, the right middle lobe, the right lower lobe, and the left lower lobe.
Figure 2
Figure 2
A chest computed tomography scan performed 2 years later in the studied patient showing an increased extent of the nodules, particularly in the right middle lobe and right lower lobe, and newly developed patchy consolidation in the right lower lobe.
Figure 3
Figure 3
A chest computed tomography (CT) scan after completion of treatment for Segniliparus rugosus infection showing a decreased extent of the nodules compared with that in the previous CT scan and the disappearance of consolidation.
See this image and copyright information in PMC

References

    1. Butler WR, Floyd MM, Brown JM, Toney SR, Daneshvar MI, Cooksey RC, et al. Novel mycolic acid-containing bacteria in the family Segniliparaceae fam. nov., including the genus Segniliparus gen. nov., with descriptions of Segniliparus rotundus sp. nov. and Segniliparus rugosus sp. nov. Int J Syst Evol Microbiol. 2005;55(Pt 4):1615–1624. - PubMed
    1. Butler WR, Sheils CA, Brown-Elliott BA, Charles N, Colin AA, Gant MJ, et al. First isolations of Segniliparus rugosus from patients with cystic fibrosis. J Clin Microbiol. 2007;45:3449–3452. - PMC - PubMed
    1. Hansen T, Van-Kerckhof J, Jelfs P, Wainwright C, Ryan P, Coulter C. Segniliparus rugosus infection, Australia. Emerg Infect Dis. 2009;15:611–613. - PMC - PubMed
    1. Koh WJ, Choi GE, Lee SH, Park YK, Lee NY, Shin SJ. First case of Segniliparus rotundus pneumonia in a patient with bronchiectasis. J Clin Microbiol. 2011;49:3403–3405. - PMC - PubMed
    1. Choi SM, Kang HJ, Jeong YJ, Lim JH, Choe WS, Hwang SH, et al. First isolation of Segniliparus rugosus from a patient with radiologic features similar to non-tuberculous mycobacteriosis. Tuberc Respir Dis. 2012;72:82–87.