Comment on

• IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration.

  Doyle SL, Ozaki E, Brennan K, Humphries MM, Mulfaul K, Keaney J, Kenna PF, Maminishkis A, Kiang AS, Saunders SP, Hams E, Lavelle EC, Gardiner C, Fallon PG, Adamson P, Humphries P, Campbell M. Doyle SL, et al. Sci Transl Med. 2014 Apr 2;6(230):230ra44. doi: 10.1126/scitranslmed.3007616. Sci Transl Med. 2014. PMID: 24695684 Free PMC article.
• IL-18 is not therapeutic for neovascular age-related macular degeneration.

  Hirano Y, Yasuma T, Mizutani T, Fowler BJ, Tarallo V, Yasuma R, Kim Y, Bastos-Carvalho A, Kerur N, Gelfand BD, Bogdanovich S, He S, Zhang X, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Nagai H, Haro I, Núñez G, Ambati BK, Hinton DR, Ambati J. Hirano Y, et al. Nat Med. 2014 Dec;20(12):1372-5. doi: 10.1038/nm.3671. Nat Med. 2014. PMID: 25473914 Free PMC article. No abstract available.