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Multicenter Study
. 2015 May;35(5):373-8.
doi: 10.1038/jp.2014.217. Epub 2014 Dec 4.

Serial aEEG recordings in a cohort of extremely preterm infants: feasibility and safety

A S Davis  1 , M G Gantz  2 , B Do  2 , S Shankaran  3 , S E G Hamrick  4 , K A Kennedy  5 , J E Tyson  5 , L F Chalak  6 , A R Laptook  7 , R F Goldstein  8 , S R Hintz  1 , A Das  9 , R D Higgins  10 , M B Ball  1 , E C Hale  4 , K P Van Meurs  1 ; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
Collaborators, Affiliations
Multicenter Study

Serial aEEG recordings in a cohort of extremely preterm infants: feasibility and safety

A S Davis et al. J Perinatol. 2015 May.

Abstract

Objective: Amplitude-integrated electroencephalography (aEEG) monitoring is increasing in the neonatal population, but the safety and feasibility of performing aEEG in extremely preterm infants have not been systematically evaluated.

Study design: Inborn infants 23(0/7) to 28(6/7) weeks gestation or birth weight 401 to 1000 g were eligible. Serial, 6-h aEEG recordings were obtained from first week of life until 36 weeks postmenstrual age. Adverse events were documented, and surveys evaluated the impact of the aEEGs on routine care. Success of performing aEEGs according to protocol and aEEG quality were assessed.

Result: A total of 102 infants were enrolled, with 755 recordings performed. 83% of recordings were performed according to schedule, and 96% were without adverse event. Bedside nurses reported no interference with routine care for 89% of recordings. 92% of recordings had acceptable signal quality.

Conclusion: Serial aEEG monitoring is safe in preterm infants, with few adverse events and general acceptance by nursing staff.

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Conflict of interest statement

CONFLICT OF INTEREST

The authors do not declare any conflicts of interest, financial or otherwise.

Figures

Figure 1
Figure 1
Patient flow diagram detailing number of infants screened, eligible, enrolled, and reasons for non-consent.
See this image and copyright information in PMC

References

    1. Maynard D, Prior PF, Scott DF. A continuous monitoring device for cerebral activity. Electroencephalogr Clin Neurophysiol. 1969;27:672–673. - PubMed
    1. Glass HC, Bonifacio SL, Peloquin S, Shimotake T, Sehring S, Sun Y, et al. Neurocritical care for neonates. Neurocrit Care. 2010;12:421–429. - PMC - PubMed
    1. Hellstrom-Westas L, Rosen I. Continuous brain-function monitoring: state of the art in clinical practice. Semin Fetal Neonatal Med. 2006;11(6):503–511. - PubMed
    1. Glass HC, Kan J, Bonifacio SL, Ferriero DM. Neonatal seizures: treatment practices among term and preterm infants. Pediatr Neurol. 2012;46:111–115. - PMC - PubMed
    1. Toet MC, Hellstrom-Westas L, Groenendaal F, Eken P, de Vries LS. Amplitude integrated EEG 3 and 6 hours after birth in full term neonates with hypoxic-ischemic encephalopathy. Arch Dis Child Fetal Neonatal Ed. 1999;81:F19–F23. - PMC - PubMed

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