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. 2015 Apr;36(4):2815-9.
doi: 10.1007/s13277-014-2908-7. Epub 2014 Dec 5.

Augmented TGFβ receptor signaling induces apoptosis of pancreatic carcinoma cells

Chenggang Li  1 , Zhiming Zhao, Zhipeng Zhou, Rong Liu
Affiliations
Free article

Augmented TGFβ receptor signaling induces apoptosis of pancreatic carcinoma cells

Chenggang Li et al. Tumour Biol. 2015 Apr.
Free article

Retraction in

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is an extremely malignant tumor in humans. Thus, understanding the tumorigenesis of PDAC appears to help develop efficient therapy. Here, we show that activated TGFβ receptor signaling induces apoptosis of pancreatic carcinoma cells in vitro and in vivo, suggesting that activation of TGFβ receptor signaling may prevent development of PDAC.

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References

    1. Genes Dev. 2001 Dec 15;15(24):3243-8 - PubMed
    1. Nature. 2010 Feb 4;463(7281):676-80 - PubMed
    1. Cell. 2008 Jul 25;134(2):215-30 - PubMed
    1. Cancer Sci. 2014 Jul;105(7):755-62 - PubMed
    1. Int J Cancer. 1975 May 15;15(5):741-7 - PubMed

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