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. 2014:2014:231081.
doi: 10.1155/2014/231081. Epub 2014 Nov 13.

Fatal Pulmonary Tumor Embolic Microangiopathy in Young Lady without Known Primary Malignancy

Adel Hammodi  1 , M Ali Al-Azem  2 , Ahmed Hanafy  1 , Talal Nakkar  1
Affiliations

Fatal Pulmonary Tumor Embolic Microangiopathy in Young Lady without Known Primary Malignancy

Adel Hammodi et al. Case Rep Crit Care. 2014.

Abstract

Pulmonary embolism (PE) is a common cause of morbidity and mortality in hospitalized patients. Malignancy, prolonged recumbence, and chemotherapy are renowned risk factors for development of clinically significant PE. Cancer exerts a multitude of pathophysiological processes, for example, hypercoagulability and abnormal vessels with sluggish circulation that can lead to PE. One of the peculiar characteristics of tumor cells is their ability to reach the circulation and behave as blood clot-not a metastasis-occluding the pulmonary circulation. We present a case of fatal pulmonary embolism diagnosed histologically to be due to tumor cell embolism.

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