A Prospective Study of Comparison of APACHE-IV & SAPS-II Scoring Systems and Calculation of Standardised Mortality Rate in Severe Sepsis and Septic Shock Patients
- PMID: 25478384
- PMCID: PMC4253202
- DOI: 10.7860/JCDR/2014/9925.5052
A Prospective Study of Comparison of APACHE-IV & SAPS-II Scoring Systems and Calculation of Standardised Mortality Rate in Severe Sepsis and Septic Shock Patients
Abstract
Context: Severe sepsis and septic shock are major causes of mortality in the Intensive Care Unit (ICU) Illness Scoring Systems can help in the prediction of outcome of these patients.
Aim: To calculate and compare APACHE-IV and SAPS-II Scoring Systems along with calculation of Standardised Mortality Rate (SMR) in patients of severe sepsis and septic shock in the ICU.
Study design: Observational-analytical prospective study.
Materials and methods: The study was conducted on 84 patients with severe sepsis and septic shock admitted to the Medical ICU of a tertiary care teaching hospital.
Results: Mean of Predicted Mortality Rate (PMR) for APACHE-IV was 37.85% and for SAPS-II, it was 72.36% which shows that APACHE-IV had under-predicted overall mortality while SAPS-II had over-predicted overall mortality of patients with severe sepsis and septic shock. Standardised Mortality Rate for APACHE-IV was 1.60 and for SAPS-II, it was 0.83.
Conclusion: Predicted Mortality of APACHE-IV and SAPS-II Scoring Systems did not correlate with the observed mortality for patients with severe sepsis and septic shock.
Keywords: APACHE-IV; SAPS-II; Septic shock; Severe sepsis; Standardised mortality rate.
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References
-
- Rangel-Frausto MS. The epidemiology of bacterial sepsis. Infect Dis Clin North Am. 1999;13:299–312. - PubMed
-
- Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome and associated costs of care. Crit Care Med. 2001;29:1303–10. - PubMed
-
- Angus DC, Wax RS. Epidemiology of sepsis: an update. Crit Care Med. 2001;29(Suppl 7):S109–16. - PubMed
-
- Friedman G, Silva E, Vincent JL. Has the mortality of septic shock changed with time? Crit Care Med. 1998;26:2078–86. - PubMed
-
- Lemeshow S, Le Gall Jr. Modelling the severity of illness of ICU patients. JAMA. 1994;272:1049–55. - PubMed
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