Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Aug;2(3):114-20.
doi: 10.5812/cardiovascmed.10332. Epub 2013 Jul 31.

Assessment of Inter and Intra-atrial Asynchrony in Patients with Systolic Heart Failure Using Velocity Vector Imaging

Maryam Esmaeilzadeh  1 , Marzieh Nikparvar  2 , Majid Maleki  1 , Feridoun Noohi  1 , Zahra Ojaghi Haghighi  1 , Niloufar Samiei  1 , Paridokht Nakhostin-Davari  1 , Hooman Bakhshandeh  3
Affiliations

Assessment of Inter and Intra-atrial Asynchrony in Patients with Systolic Heart Failure Using Velocity Vector Imaging

Maryam Esmaeilzadeh et al. Res Cardiovasc Med. 2013 Aug.

Abstract

Background: According to previous studies on the deformation properties of the left atrium, the systolic strain and strain rates represent the atrial reservoir function and the early and late diastolic strain rates show the conduit and booster functions, respectively.

Objectives: We sought to evaluate the intra and interatrial asynchrony using strain/strain rate imaging in systolic heart failure patients.

Patients and methods: Twenty five patients with systolic heart failure (LVEF ≤ 40%) were enrolled into the study. Asynchrony quantifications were performed according to the standard deviation of time-to peak (TP-SD) of deformation of three segments manually located along the perimeter of the left atrium free wall, right atrium free wall and interatrial septum, as imaged in an apical four-chamber view. We also calculated classic echocardiography parameters such as LV end-diastolic dimension index, LA volume index, RA area, as well as deceleration time (DT) on transmitral pulsed wave Doppler and E/E' ratio on mitral annular tissue Doppler imaging.

Results: In heart failure patients either inter or intra-atrial asynchrony were far more common in comparison with normal subjects (P=0.008 and P=0.007 respectively).

Conclusions: Left ventricular systolic heart failure, may result in inter and intra-atrial asynchrony even in clinically stable patients without significant pulmonary hypertension and diastolic dysfunction.

Keywords: Asynchrony; Heart Failure; Strain.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.. Atrial Strain and Strain Rate Curves of a Normal Subject
Figure 2.
Figure 2.. Schematic Atrial Strain (Left) and Strain Rate (Right) Curves
Figure 3.
Figure 3.. Evaluation of Atrial Deformation According to the Speckle-tracking Technique. Left Atrial (top) and Right Atrial (bottom) Endocardial Contour is Traced in a Four-chamber View
Figure 4.
Figure 4.. Comparison of Inter-atrial Asynchrony by Strain Rate Measurements in Heart Failure Patients and Control Group
Figure 5.
Figure 5.. Correlation Between Corrected Interatrial Asynchrony (Strain Rate Measurements) and Systolic Pulmonary Artery Pressure, P = 0.022, r = 0.5
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Van Beeumen K, Duytschaever M, Tavernier R, Van de Veire N, De Sutter J. Intra- and interatrial asynchrony in patients with heart failure. Am J Cardiol. 2007;99(1):79–83. doi: 10.1016/j.amjcard.2006.07.066. - DOI - PubMed
    1. Kuppahally SS, Akoum N, Burgon NS, Badger TJ, Kholmovski EG, Vijayakumar S, et al. Left atrial strain and strain rate in patients with paroxysmal and persistent atrial fibrillation: relationship to left atrial structural remodeling detected by delayed-enhancement MRI. Circ Cardiovasc Imaging. 2010;3(3):231–9. doi: 10.1161/CIRCIMAGING.109.865683. - DOI - PubMed
    1. Cameli M, Caputo M, Mondillo S, Ballo P, Palmerini E, Lisi M, et al. Feasibility and reference values of left atrial longitudinal strain imaging by two-dimensional speckle tracking. Cardiovasc Ultrasound. 2009;7:6. doi: 10.1186/1476-7120-7-6. - DOI - PMC - PubMed
    1. Azar F, Perez de Isla L, Moreno M, Landaeta A, Refoyo E, Lopez Fernandez T, et al. Three-dimensional echocardiographic assessment of left atrial size and function and the normal range of asynchrony in healthy individuals. Rev Esp Cardiol. 2009;62(7):816–9. - PubMed
    1. Dell'Era G, Rondano E, Franchi E, Marino PN. Atrial asynchrony and function before and after electrical cardioversion for persistent atrial fibrillation. Eur J Echocardiogr. 2010;11(7):577–83. doi: 10.1093/ejechocard/jeq010. - DOI - PubMed

LinkOut - more resources