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Comment
. 2014 Dec 4;15(6):671-3.
doi: 10.1016/j.stem.2014.11.008.

Patching up broken hearts: cardiac cell therapy gets a bioengineered boost

Vahid Serpooshan  1 , Sean M Wu  2
Affiliations
Comment

Patching up broken hearts: cardiac cell therapy gets a bioengineered boost

Vahid Serpooshan et al. Cell Stem Cell. .

Abstract

Preclinical and clinical studies for cardiac cell therapy have only seen moderate success due to poor engraftment and survival of transplanted cells. In this issue of Cell Stem Cell, Ye et al. (2014) employ a growth-factor-loaded fibrin patch and show improved cardiovascular cell survival after cell transplantation into a porcine model of ischemia reperfusion.

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Figures

Figure 1.
Figure 1.. Comparison of Cardiovascular Cell Survival with and without a Tissue-Engineered Patch
Schematic diagram of the experiments conducted by Ye et al. (2014) and the reported outcomes from the injection of trilineage cardiac cells derived from hiPSCs with and without an IGF-1-loaded epicardial fibrin patch.
See this image and copyright information in PMC

Comment on

References

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