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Review
. 2015 Feb;62(2):100-5.
doi: 10.1016/j.endonu.2014.10.007. Epub 2014 Dec 4.

Bone and metabolic complications of urinary diversions

[Article in English, Spanish]
Marta Cano Megías  1 , Eva Golmayo Muñoz Delgado  2
Affiliations
Review

Bone and metabolic complications of urinary diversions

[Article in English, Spanish]
Marta Cano Megías et al. Endocrinol Nutr. 2015 Feb.

Abstract

Hyperchloremic metabolic acidosis is a complication of urinary diversion using ileum or colon. Its prevalence ranges from 25% and 46% depending on the procedure used and renal function of the patient. It is a consequence of intestinal fluid and electrolyte exchange between intestinal mucosa and urine. The main mechanism is absorption of ammonium and chloride from urine. Long-term chronic metabolic acidosis in these patients may lead to impaired bone metabolism and osteomalacia. Regular monitoring of pH, chlorine, bicarbonate, and calcium-phosphorus metabolism is therefore essential for early diagnosis and treatment.

Keywords: Acidosis metabólica; Conducto ileal; Derivación urinaria; Hipopotasemia; Hypokalemia; Ileal conduit; Metabolic acidosis; Neobladder; Neovejiga; Urinary diversion.

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