Bone and metabolic complications of urinary diversions

Abstract

Hyperchloremic metabolic acidosis is a complication of urinary diversion using ileum or colon. Its prevalence ranges from 25% and 46% depending on the procedure used and renal function of the patient. It is a consequence of intestinal fluid and electrolyte exchange between intestinal mucosa and urine. The main mechanism is absorption of ammonium and chloride from urine. Long-term chronic metabolic acidosis in these patients may lead to impaired bone metabolism and osteomalacia. Regular monitoring of pH, chlorine, bicarbonate, and calcium-phosphorus metabolism is therefore essential for early diagnosis and treatment.

Keywords: Acidosis metabólica; Conducto ileal; Derivación urinaria; Hipopotasemia; Hypokalemia; Ileal conduit; Metabolic acidosis; Neobladder; Neovejiga; Urinary diversion.