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Review
. 2015 Jan;40(1):238-9.
doi: 10.1038/npp.2014.206.

In vivo calcium imaging to illuminate neurocircuit activity dynamics underlying naturalistic behavior

Shanna L Resendez  1 , Garret D Stuber  1
Affiliations
Review

In vivo calcium imaging to illuminate neurocircuit activity dynamics underlying naturalistic behavior

Shanna L Resendez et al. Neuropsychopharmacology. 2015 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Optical technologies for in vivo calcium imaging in freely behaving mice. (a) Mini-epifluorescence microscope attached to a head-mounted base plate that is centered around a microendoscope implanted above a brain region of interest. (b) A fiber probe is implanted above the target brain region of interest to collect bulk changes in calcium-mediated fluorescence using fiber photometry. (c) Animals engaging in naturalistic behavior such as social interaction while fluorescent transients are measured as a read-out of neural activity with the use of microendoscopic imaging (left) or fiber photometry (right).
See this image and copyright information in PMC

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References

    1. Chen T-W, Wardill TJ, Sun Y, Pulver SR, Renninger SL, Baohan A et al (2013). Ultrasensitive fluorescent proteins for imaging neuronal activity. Nature 499: 295–300. - PMC - PubMed
    1. Cui G, Jun SB, Jin X, Pham MD, Vogel SS, Lovinger DM et al (2013). Concurrent activation of striatal direct and indirect pathways during action initiation. Nature 494: 238–242. - PMC - PubMed
    1. Gunaydin LA, Grosenick L, Finkelstein JC, Kauvar IV, Fenno LE, Adhikari A et al (2014). Natural neural projection dynamics underlying social behavior. Cell 157: 1535–1551. - PMC - PubMed
    1. Jennings JH, Stuber GD (2014). Tools for resolving functional activity and connectivity within intact neural circuits. Curr Biol 24: R41–R50. - PMC - PubMed
    1. Svoboda K, Yasuda R (2006). Principles of two-photon excitation microscopy and its applications to neuroscience. Neuron 50: 823–839. - PubMed

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