Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015;29(8):739-44.
doi: 10.1080/14786419.2014.985678. Epub 2014 Dec 6.

A new naphthoquinone and other antibacterial constituents from the roots of Xanthium sibiricum

Wen-Hao Chen  1 , Wen-Jie Liu, Yan Wang, Xiao-Ping Song, Guang-Ying Chen
Affiliations

A new naphthoquinone and other antibacterial constituents from the roots of Xanthium sibiricum

Wen-Hao Chen et al. Nat Prod Res. 2015.

Abstract

Reinvestigating the chemical constituents of the roots of Xanthium sibiricum led to the isolation of a new naphthoquinone (1), together with 13 known compounds (2-14). Their structures were elucidated by using spectroscopic analyses, including HR-ESI-MS, 1D and 2D NMR, and by comparing their NMR data with those of related compounds. Compound 1 showed moderate antibacterial activity against Escherichia coli, Bacillus subtilis, Micrococcus tetragenus and Staphylococcus aureus, while 6 and 12 showed stronger antibacterial activity than the positive control ciprofloxacin against E. coli, with minimum inhibitory concentration values of 0.17 and 0.35 μg/mL, respectively.

Keywords: Xanthium sibiricum Patr; antibacterial activity; chemical constituents; compositae.

PubMed Disclaimer

Publication types

MeSH terms