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Review
. 2014;5(4):e964559.
doi: 10.4161/21541264.2014.964559. Epub 2014 Oct 31.

Regulatory SNPs and transcriptional factor binding sites in ADRBK1, AKT3, ATF3, DIO2, TBXA2R and VEGFA

Norman E Buroker  1
Affiliations
Review

Regulatory SNPs and transcriptional factor binding sites in ADRBK1, AKT3, ATF3, DIO2, TBXA2R and VEGFA

Norman E Buroker. Transcription. 2014.

Abstract

Abstract Regulatory single nucleotide polymorphisms (rSNPs) which change the transcriptional factor binding sites (TFBS) for transcriptional factors (TFs) to bind DNA were reviewed for the ADRBK1 (GRK2), AKT3, ATF3, DIO2, TBXA2R and VEGFA genes. Changes in the TFBS where TFs attach to regulate these genes may result in human sickness and disease. The highlights of this previous work were reviewed for these genes.

Keywords: ADRBK1; AKT3; ATF3; DIO2; TBXA2R and VEGFA genes; rSNPs; transcriptional factor binding site; transcriptional factors.

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