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. 2014 Dec;87(6):298-303.
doi: 10.4174/astr.2014.87.6.298. Epub 2014 Nov 28.

Gastrointestinal stromal tumors (GISTs) of the stomach: a multicenter, retrospective study of curatively resected gastric GISTs

In-Hwan Kim  1 , In-Ho Kim  1 , Sang-Gyu Kwak  2 , Se Won Kim  3 , Hyun-Dong Chae  1
Affiliations

Gastrointestinal stromal tumors (GISTs) of the stomach: a multicenter, retrospective study of curatively resected gastric GISTs

In-Hwan Kim et al. Ann Surg Treat Res. 2014 Dec.

Abstract

Purpose: The standard treatment for primary localized gastric gastrointestinal stromal tumor (GIST) is surgical resection. The clinical behavior of gastric GIST after surgical resection is extremely variable. We conducted a multicenter, retrospective study of gastric GISTs patients who underwent curative surgical resection to evaluate clinical features and the prognosis of surgically treated gastric GISTs.

Methods: We performed a retrospective study on 406 consecutive patients who underwent curative resections for localized gastric GIST at four university hospitals in Daegu, Korea, between March 1998 and March 2012. The retrospectively collected medical records were reviewed with respect to clinical parameters including age, gender, tumor location, surgical approach, and recurrence.

Results: There were 406 patients: 157 males (38.7%) and 249 females (61.3%), with a mean age of 60.8 ± 10.8 (standard deviation) years. The mean tumor size was 4.9 cm (range, 0.3-29 cm). Curative surgical resection was performed in all patients without tumor rupture or spillage. Laparoscopic wedge resections were performed in 156 patients (38.4%) and open resections in 250 patients (61.6%). The tumor size of the laparoscopic wedge resection group was smaller than that of open resection group (3.45 cm vs. 5.46 cm; P < 0.001). There were 11 recurrent cases (2.7%). No recurrence was observed in patients who underwent laparoscopic wedge resections.

Conclusion: Gastric GISTs had a low recurrence rate after curative resection in our series. Laparoscopic gastric wedge resection is feasible for treating gastric GISTs in selected patients.

Keywords: Gastrointestinal stromal tumors; Laparoscopy; Prognosis; Stomach.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
Yearly changes in the proportion of open resection and laparoscopic resection for gastric gastrointestinal stromal tumors (GISTs). There showed an increasing tendency to perform laparoscopic resections for gastric GISTs.
See this image and copyright information in PMC

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