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. 2014;17(Pt 2):546-53.
doi: 10.1007/978-3-319-10470-6_68.

Rapid D-Affine biventricular cardiac function with polar prediction

Kathleen Gilbert, Brett R Cowan, Avan Suinesiaputra, Christopher Occleshaw, Alistair A Young

Rapid D-Affine biventricular cardiac function with polar prediction

Kathleen Gilbert et al. Med Image Comput Comput Assist Interv. 2014.

Abstract

Although many solutions have been proposed for left ven-tricular functional analysis of the heart, right and left (bi-) ventricular function has been problematic due to the complex geometry and large motions. Biventricular function is particularly important in congenital heart disease, the most common type of birth defects. We describe a rapid interactive analysis tool for biventricular function which incorporates 1) a 3D+ time finite element model of biventricular geometry, 2) a fast prediction step which estimates an initial geometry in a polar coordinate system, and 3) a Cartesian update which penalizes deviations from affine transformations (D-Affine) from a prior. Solution times were very rapid, enabling interaction in real time using guide point modeling. The method was applied to 13 patients with congenital heart disease and compared with the clinical gold standard of manual tracing. Results between the methods showed good correlation (R2 > 0.9) and good precision (volume < 17 ml; mass < 11g) for both chambers.

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Figures

Fig. 1
Fig. 1
Examples of short axis frames at end-diastole from MR cines from three different CHD patients (left: atrial septal defect, partial anomalous pulmonary venous drainage and pulmonary hypertension, middle: teratology of Fallot and, right: dextotransposition of the great arteries). The RV is the chamber on the left hand side (yellow/orange). Note the wide variation of shapes in these examples. Contours were generated by intersection of model with image plane. The arrow refers to in-plane shift due to correction of breath-hold mis-registration.
Fig. 2
Fig. 2
Finite element model showing four valves and element boundaries. Model coordinates (ξ1, ξ2, ξ3) were defined as shown.
Fig. 3
Fig. 3
Comparison of LVEDV, RVEDV, LVESV, RVEDV, and mass with the gold standard Argus
Fig. 4
Fig. 4
Bland–Altman plots for LVEDV, RVEDV, LVESV, RVEDV, and mass. The red lines represent 2 standard deviations from the mean. The interobserver error for Argus is shown in green (mean ± 2 standard devations).
See this image and copyright information in PMC

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