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Comment
. 2014;13(21):3313-4.
doi: 10.4161/15384101.2014.972918.

Defining cellular identity through network biology

Patrick Cahan  1 , Samantha A Morris, James J Collins, George Q Daley
Affiliations
Comment

Defining cellular identity through network biology

Patrick Cahan et al. Cell Cycle. 2014.
No abstract available

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Figures

Figure 1.
Figure 1.
The establishment of a lineage specific gene regulatory network (GRN) in development (left), in directed differentiation of pluripotent stem cells (middle), and in direct conversion (right). Cell engineering approaches fail to fully install the hepatocyte GRN, fail to decommission the starting cell type GRN, and partially establish alternate fate GRNs.
See this image and copyright information in PMC

Comment on

References

    1. Cahan P, et al. 2014; 158:903–15; - PMC - PubMed
    1. Morris SA, et al. Cell 2014; 158:889–902; - PMC - PubMed

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