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. 2014 Dec;19(12):120501.
doi: 10.1117/1.JBO.19.12.120501.

Single-shot speckle noise reduction by interleaved optical coherence tomography

Lian Duan, Hee Yoon Lee, Gary Lee, Monica Agrawal, Gennifer T Smith, Audrey K Ellerbee

Single-shot speckle noise reduction by interleaved optical coherence tomography

Lian Duan et al. J Biomed Opt. 2014 Dec.

Abstract

Speckle noise is one of the dominant factors that degrade image quality in optical coherence tomography (OCT). Here, we propose a new strategy, interleaved OCT (iOCT), for spatial compounding and angular compounding. We demonstrate the efficiency of compounding with iOCT to restrain speckle noise without compromising imaging speed in phantoms and tissue samples.

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