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. 2014 Dec 8;26(6):940-940.e1.
doi: 10.1016/j.ccell.2014.11.015.

SnapShot: Medulloblastoma

Jessica M Rusert  1 , Xiaochong Wu  2 , Charles G Eberhart  3 , Michael D Taylor  2 , Robert J Wechsler-Reya  1
Affiliations

SnapShot: Medulloblastoma

Jessica M Rusert et al. Cancer Cell. .

Abstract

Medulloblastoma (MB) is the most common malignant brain tumor in children, where one-third of patients succumb to their disease. This SnapShot describes the classification of MB subgroups, historically by histopathology and currently based on genomic information. Genomics-based classification has identified four major subgroups and provides greater opportunity for developing targeted therapies more successful than current conventional therapy.

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References

    1. Adamski J, Ramaswamy V, Huang A, Bouffet E. F1000Prime Rep. 2014;6:56. - PMC - PubMed
    1. Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, et al. Nature. 2010;468:1095–1099. - PMC - PubMed
    1. Gilbertson RJ, Ellison DW. Annu Rev Pathol. 2008;3:341–365. - PubMed
    1. Hovestadt V, Jones DT, Picelli S, Wang W, Kool M, Northcott PA, Sultan M, Stachurski K, Ryzhova M, Warnatz HJ, et al. Nature. 2014;510:537–541. - PubMed
    1. Kool M, Jones DT, Jäger N, Northcott PA, Pugh TJ, Hovestadt V, Piro RM, Esparza LA, Markant SL, Remke M, et al. ICGC PedBrain Tumor Project . Cancer Cell. 2014;25:393–405. - PMC - PubMed

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