The occurrence of nicotinamide adenine dinucleotide glycohydrolase and the serum opacity reaction in groups B, C, F and G streptococci

Abstract

The frequency of the serum opacity reaction (SOR) and nicotinamide adenine dinucleotide glycohydrolase (NADase) production in non-A groups of beta-haemolytic streptococci isolated from humans and animals was surveyed. The SOR was positive with five of eighteen group B isolates (28%), four of fifteen group C (27%), two of five group F (40%), and thirty-seven of sixty-eight group G (54%) isolates. NADase activity, in addition to SOR, was found in three of eighteen group B isolates (17%), three of fifteen group C (20%), forty of sixty-eight group G (59%), and none of the group F isolates. The SOR was produced by forty-eight (45%) and NADase was produced by fifty-one (48%) of the one hundred and six isolates of non-group A beta-haemolytic streptococci. Twenty-five percent of the isolates were both NADase and SOR positive.