Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Mar-Apr;23(2):491-501.

[Effect of camptothecin on the DNA-relaxing and DNA-cleavage activity of calf thymus topoisomerase I]

[Article in Russian]
I B Bronshteĭn, I I Gromova, V L Bukhman, K A Kafiani
  • PMID: 2549395

[Effect of camptothecin on the DNA-relaxing and DNA-cleavage activity of calf thymus topoisomerase I]

[Article in Russian]
I B Bronshteĭn et al. Mol Biol (Mosk). 1989 Mar-Apr.

Abstract

Nucleotide sequences that are cleaved by calf thymus type I topoisomerase have been determined using cloned human Ha-ras and p53 genes. Localization and relative frequency of single-strand cleavages within these sequences were observed to change in the presence of the cytotoxic alkaloid camptothecin.

PubMed Disclaimer

Publication types

LinkOut - more resources