Progesterone for traumatic brain injury--resisting the sirens' song

Affiliations

¹ From the Department of Neurology, TeleStroke and Acute Stroke Services, and Institute for Heart, Vascular, and Stroke Care, Massachusetts General Hospital, and the Department of Neurology, Harvard Medical School - both in Boston.

Editorial

Lee H Schwamm. N Engl J Med. 2014.

. 2014 Dec 25;371(26):2522-3.

doi: 10.1056/NEJMe1412951. Epub 2014 Dec 10.

¹ From the Department of Neurology, TeleStroke and Acute Stroke Services, and Institute for Heart, Vascular, and Stroke Care, Massachusetts General Hospital, and the Department of Neurology, Harvard Medical School - both in Boston.

No abstract available

Comment on

Very early administration of progesterone for acute traumatic brain injury.
Wright DW, Yeatts SD, Silbergleit R, Palesch YY, Hertzberg VS, Frankel M, Goldstein FC, Caveney AF, Howlett-Smith H, Bengelink EM, Manley GT, Merck LH, Janis LS, Barsan WG; NETT Investigators. Wright DW, et al. N Engl J Med. 2014 Dec 25;371(26):2457-66. doi: 10.1056/NEJMoa1404304. Epub 2014 Dec 10. N Engl J Med. 2014. PMID: 25493974 Free PMC article. Clinical Trial.
A clinical trial of progesterone for severe traumatic brain injury.
Skolnick BE, Maas AI, Narayan RK, van der Hoop RG, MacAllister T, Ward JD, Nelson NR, Stocchetti N; SYNAPSE Trial Investigators. Skolnick BE, et al. N Engl J Med. 2014 Dec 25;371(26):2467-76. doi: 10.1056/NEJMoa1411090. Epub 2014 Dec 10. N Engl J Med. 2014. PMID: 25493978 Clinical Trial.